May 7, 2024
Conference Paper

Expanding the access of wearable silicone wristbands in community-engaged research through best practices in data analysis and integration

Abstract

Wearable silicone wristbands are a rapidly growing exposure assessment technology that offer researchers the ability to study previously inaccessible cohorts and have the potential to provide a more comprehensive picture of chemical exposure within diverse communities. However, there are no established best practices for analyzing the data within a study or across multiple studies, thereby limiting impact and access of these data for larger meta-analyses. We utilize data from three studies, from over 600 wristbands worn by participants in New York City and Eugene, Oregon, to present a first-of-its-kind manuscript detailing wristband data properties. We further discuss and provide concrete examples of key areas and considerations in common statistical modeling methods where best practices must be established to enable meta-analyses and integration of data from multiple studies. Finally, we detail important and challenging aspects of machine learning, meta-analysis, and data integration that researchers will face in order to extend beyond the limited scope of individual studies focused on specific populations.

Published: May 7, 2024

Citation

Bramer L.M., H.M. Dixon, D.J. Degnan, D. Rohlman, J.B. Herbstman, K.A. Anderson, and K.M. Waters. 2024. Expanding the access of wearable silicone wristbands in community-engaged research through best practices in data analysis and integration. In Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing (Biocomputing 2024), January 3-7, 2024, Kohala Coast, HI, edited by R.B. Altman, L. Hunter, M.D. Ritchie, and T. Murray, 170-186. PNNL-SA-188524. doi:10.1142/9789811286421_0014

Research topics